A 1-0 victory over Parma last weekend allowed Inter to move above Rome into fifth place in Serie A and kickstart their challenge for a Champions League qualification place. Palermo, meanwhile, drew 1-1 away to Catania which means they sit in the relegation zone in 18th, with just five league matches left to play.
Despite that victory, the pressure continues to mount on Inter coach Andrea Stramaccioni, with his team having endured a poor run of form in recent months. They currently sit five points off fourth-placed Fiorentina.
Tommaso Rocchi is expected to continue up front for the Nerazzurri after scoring the vital late goal that sealed their victory last week, while Samir Handanovic will start in goal despite rumours this week linking him with a move to Barcelona.
The San Siro side have a huge injury list to contend with ahead of their match against an in-form Palermo, with a number of first-team players still on the sidelines. Antonio Cassano, Diego Milito, Rodrigo Palacio, Esteban Cambiasso and Walter Gargano are all still out.
Josip Ilicic netted Palermo's 95th minute equaliser against Catania in their last league game, and should retain his place in attack for the hosts.
The Sicilians are without the suspended Andrea Dossena, but are otherwise largely at full strength as they seek to clamber out of the relegation places.
